This policy briefing examines issues around climate change and migration in the renewed UN–AU partnership. It notes that climate change and migration are particularly problematic for any sustainable development efforts in Africa. Despite the adoption of the Joint UN–AU Framework for Enhanced Partnership in Peace and Security in 2017 and the subsequent finalisation of the AU–UN Framework on Implementation of Agenda 2063 and Agenda 2030 barely a year later, the two organisations still lack a common position on how best to respond to the challenges of climate change and human mobility in Africa. To ensure an effective partnership in these two areas, the AU and the UN need to engage more closely and in a coherent manner.