Countries in the wider Horn of Africa security complex are experiencing increasing involvement from external economic and security actors. Several countries, multinationals, and non-state armed groups have set up shop, influencing existing dynamics between and within the target countries in the region. These target countries include Central African Republic (CAR), Democratic Republic of the Congo (DRC), Somalia, and South Sudan. Interestingly, all these countries are experiencing one form of conflict or another. In their engagements with these countries, foreign businesses and states should take note of the UN Guiding Principles on Business and Human Rights, the Paris Principles, and UN Human Rights Council Resolution A/HRC/RES/17/4, adopt effective human rights due diligence, and ensure that their policies and legislation are effective in preventing human rights violations by external economic involvement.