Senegal, like other African countries, has been hit by Covid-19 and has put in place measures to contain the epidemic. These measures impact men and women differently. To capture their effects on women’s employment, we use a computable general equilibrium model, coupled with a micro-simulation module. The results show that the Senegalese economy suffers from these measures with a decrease in GDP by 5.38% in the moderate scenario. In terms of employment, the informal sector is more heavily affected than the formal sector, as some businesses benefit from the increase in foreign demand for certain agricultural products. Unskilled workers are the most affected group by the crisis. Although women are strongly affected, they are relatively less affected than men. This is due to the predominant presence of women in the agricultural sectors, which are positively impacted by the increase in foreign demand for agricultural products.