The Lake Chad Basin Region (LCBR), which basically consists of fringe territories in Nigeria, Niger, Chad and Cameroon, is notoriously fragile and highly unstable. The region is largely characterised by violent extremism and cross-border crimes. With the outbreak of COVID-19 pandemic and it’s spread to LCBR in early 2020, it is expected that the impact of the disease would transcend health. It will also impact the socio-economic conditions of the area and this will complicate the already fragile peace and security landscape of LCBR. This policy brief takes a look at the nature of COVID-19 pandemic in LCBR and its implication for the fragile peace and security landscape of the region. It ends with some recommendations.